Aspartate aminotransferase-platelet ratio index, adiponectin and body mass index in children with fatty liver

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Aspartate aminotransferase-platelet ratio index, adiponectin and body mass index in children with fatty liver

Obesity in children is becoming a global epidemic. Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent and potentially serious complication of childhood obesity. Adiponectin level was decreased on obese children. Adiponectin is a protective factor against non-alcoholic fatty liver disease on obesity. The early identification of fibrosis is important in children with NAFLD in order to...

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Assessment of liver fibrosis and cirrhosis by aspartate aminotransferase-to-platelet ratio index in children with biliary atresia.

BACKGROUND In patients with biliary atresia (BA), liver fibrosis and cirrhosis commonly occur even after Kasai hepatoportoenterostomy. Although liver biopsy is the gold standard to evaluate liver fibrosis, it is invasive and may result in life-threatening complications. The aspartate aminotransferase-to-platelet ratio index (APRI) is a safe and simple method to assess liver fibrosis in patients...

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Aspartate aminotransferase to platelet ratio index for the assessment of liver fibrosis severity in patients with chronic hepatitis

Sirli R, Sporea I. Aspartate aminotransferase to platelet ratio index for the assessment of liver fibrosis severity in patients with chronic hepatitis. I read with interest the article by Yilmaz et al. regarding the value of aspartate aminotransferases (AST)–to– platelet ratio index (APRI score) for the noninvasive assessment of liver fibrosis in chronic hepatitis, which was published in Hepati...

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Aspartate aminotransferase-to-platelet ratio index for fibrosis and cirrhosis prediction in chronic hepatitis C patients.

In chronic hepatitis C (CHC), liver biopsy is the gold standard method for assessing liver histology, however it is invasive and can have complications. Non-invasive markers have been proposed and aspartate aminotransferase (AST)-to-platelet ratio index (APRI) has been shown as an easy and inexpensive marker of liver fibrosis. This study evaluated the diagnostic performance of APRI for signific...

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The aspartate aminotransferase-to-platelet ratio and the evaluation of non-alcoholic fatty liver disease

Dear Editor, We thank Agilli et al. and Kayadibi et al. for their interest in our manuscript [1]. Taken together, their letters raise points of clarification regarding the utility and general applicability of the ‘aspartate aminotransferase-to-platelet ratio index’ (APRI) test in the evaluation of liver fibrosis. Our first comment is that their concern over confounders of the APRI unrelated to ...

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ژورنال

عنوان ژورنال: International Journal of Pediatric Endocrinology

سال: 2013

ISSN: 1687-9856

DOI: 10.1186/1687-9856-2013-s1-p107